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Week 1
Tennessee @ Indianapolis (-4)
Jacksonville (-1) @ New England
New Orleans (-13) @ San Francisco
Tampa Bay @ New York (A) (even) Game of the week
Green Bay (-5) @ Denver
Chicago @ Detroit (-10)
Miami (-2) @ Buffalo
Kansas City @ Oakland (-11)
Minnesota @ Dallas (-2)
Cincinnati @ Baltimore (-5)
Philadelphia @ Washington (-2)
Carolina @ Atlanta (-16)
Los Angeles (A) @ Pittsburgh (-6)
New York (N) (-3) @ Cleveland
Seattle @ Arizona (-14)
Los Angeles (N) @ Houston (-23)
Week 2
Atlanta (-4) @ Tampa Bay
New Orleans (-12) @ New York (A)
New England @ Indianapolis (-5)
Washington @ Dallas (-2)
Cleveland (-9) @ Kansas City
Philadelphia @ Baltimore (-3)
Detroit @ Green Bay (-4)
Oakland (-2) @ Los Angeles (A)
Cincinnati @ Denver (-1)
Pittsburgh @ New York (N) (-15)
Carolina @ Chicago (-5)
Miami @ Houston (-13)
Buffalo @ Tennessee (-2)
Jacksonville @ Seattle (even) Game of the week
Arizona (-13) @ San Francisco
Los Angeles (N) @ Minnesota (-5)
Week 3
Los Angeles (N) @ New Orleans (-18)
Miami @ Atlanta (-3)
Washington @ Pittsburgh (-6)
Oakland (-5) @ Kansas City
Denver @ Cleveland (-15)
Baltimore @ Cincinnati (-1) Game of the week
Dallas @ New York (N) (-19)
Carolina @ New England (-9)
Tampa Bay @ Philadelphia (-3)
Minnesota @ Detroit (-7)
Chicago @ Los Angeles (A) (-6)
Arizona (-5) @ Green Bay
Houston (-18) @ San Francisco
Seattle @ Tennessee (-3)
Indianapolis @ Jacksonville (-5)
Buffalo (-2) @ New York (A)
Week 4
Los Angeles (N) @ Seattle (-7)
Miami @ Cleveland (-4)
Houston (-13) @ Tennessee
Arizona (-5) @ Jacksonville
Cincinnati @ New England (-5)
New York (N) (-11) @ Philadelphia
Baltimore @ Pittsburgh (-5)
Denver @ Kansas City (-3)
Los Angeles (A) @ Oakland (-8)
Green Bay (-5) @ Chicago
Minnesota @ Washington (-3)
Atlanta (-2) @ Buffalo
New Orleans (-9) @ Tampa Bay
New York (A) @ Carolina (even) Game of the week
San Francisco @ Indianapolis (-9)
Dallas @ Detroit (-8)
Week 5
Carolina @ Tampa Bay (-9)
Atlanta @ New Orleans (-8)
New York (A) @ New England (-6)
Indianapolis @ Arizona (-13)
San Francisco @ Los Angeles (N) (-4)
Seattle @ Washington (-1) Game of the week
Cleveland (-7) @ Dallas
Kansas City @ Los Angeles (A) (-6)
Denver @ Baltimore (-7)
Chicago @ Philadelphia (-7)
Detroit @ New York (N) (-14)
Minnesota @ Green Bay (-8)
Cincinnati @ Oakland (-9)
Pittsburgh @ Buffalo (-3)
Houston (-10) @ Jacksonville
Tennessee @ Miami (-9)
Week 6
Washington @ New York (N) (-18)
Jacksonville @ Indianapolis (-1)
Miami (-7) @ New York (A)
New England @ Buffalo (-5)
Arizona @ New Orleans (-3)
Tampa Bay @ Atlanta (-10)
Seattle (-1) @ Los Angeles (N) Game of the week
San Francisco @ Tennessee (-8)
Cleveland @ Houston (-12)
Los Angeles (A) @ Cincinnati (-2)
Kansas City @ Denver (-3)
Oakland (-1) @ Baltimore
Pittsburgh @ Philadelphia (-1)
Green Bay @ Detroit (-2)
Chicago @ Minnesota (-6)
Dallas (-1) @ Carolina
Week 7
Detroit (-1) @ Los Angeles (A)
Baltimore @ Dallas (-1)
Green Bay (-2) @ Washington
Philadelphia @ New York (N) (-17)
Pittsburgh @ Cleveland (-9)
Oakland @ Miami (-6)
Tennessee @ Houston (-19)
New York (A) @ Buffalo (-8)
New England @ Tampa Bay (-3)
New Orleans (-15) @ Carolina
Chicago @ Kansas City (-3)
Indianapolis (-1) @ Cincinnati
Minnesota @ Denver (even) Game of the week
Los Angeles (N) @ Jacksonville (-10)
Arizona (-8) @ Seattle
San Francisco @ Atlanta (-14)
Week 8
New York (N) (-13) @ Dallas
Pittsburgh (-1) @ Cincinnati
Atlanta @ Arizona (-8)
Tampa Bay (-1) @ San Francisco Game of the week
New Orleans (-8) @ Seattle
Houston (-10) @ Oakland
Green Bay (-2) @ Minnesota
Philadelphia @ Cleveland (-11)
Baltimore @ Washington (-2)
Detroit (-4) @ Chicago
Jacksonville (-5) @ Denver
New York (A) @ Miami (-13)
Buffalo @ Indianapolis (-3)
Carolina @ Los Angeles (N) (-6)
Los Angeles (A) @ Tennessee (-5)
New England (-1) @ Kansas City
Week 9
Minnesota @ Tampa Bay (-4)
New York (A) @ Baltimore (-6)
Oakland (-5) @ Chicago
Dallas @ Cincinnati (-3)
Los Angeles (A) @ Denver (even)
Philadelphia @ Los Angeles (N) (even) Game of the week
New York (N) @ Arizona (-1)
Tennessee @ Pittsburgh (-4)
Seattle (-4) @ Carolina
Jacksonville (-5) @ San Francisco
Cleveland (-6) @ Washington
Detroit (-4) @ Kansas City
Green Bay @ New Orleans (-11)
Atlanta (-4) @ New England
Houston (-12) @ Indianapolis
Buffalo @ Miami (-8)
Week 10
Washington @ Chicago (even) Game of the week
Indianapolis (-2) @ Los Angeles (N)
Baltimore @ Jacksonville (-7)
Dallas @ Philadelphia (-5)
New Orleans @ New York (N) (-5)
New England @ Miami (-10)
Buffalo @ Tampa Bay (-1)
Tennessee (-1) @ New York (A)
Arizona @ Houston (-8)
San Francisco @ Carolina (-1)
Seattle @ Atlanta (-9)
Cincinnati @ Cleveland (-13)
Kansas City @ Green Bay (-11)
Denver @ Detroit (-10)
Los Angeles (A) @ Minnesota (-3)
Pittsburgh @ Oakland (-5)
Week 11
Atlanta (-1) @ Detroit
Green Bay (-3) @ Dallas
Kansas City @ Indianapolis (-9)
Tampa Bay @ New Orleans (-15)
Washington @ Philadelphia (-4)
New England @ New York (A) (even) Game of the week
Baltimore @ Cleveland (-11)
Denver @ Los Angeles (A) (-6)
Cincinnati @ Pittsburgh (-7)
Chicago @ New York (N) (-21)
Miami (-10) @ Carolina
Houston (-12) @ Buffalo
Tennessee @ Jacksonville (-6)
San Francisco @ Seattle (-8)
Arizona (-12) @ Los Angeles (N)
Minnesota @ Oakland (-8)
Week 12
Denver @ New York (A) (-4)
Seattle @ Indianapolis (-4)
Jacksonville @ Houston (-16)
Tampa Bay @ Miami (-10)
Atlanta (-10) @ Carolina
Washington @ Cincinnati (-2)
Cleveland (-3) @ Pittsburgh
Baltimore (-1) @ Kansas City
New York (N) (-12) @ Minnesota
Chicago @ Green Bay (-11)
Buffalo @ Los Angeles (A) (even) Game of the week
New England @ New Orleans (-15)
Tennessee @ Arizona (-14)
Los Angeles (N) @ San Francisco (-2)
Philadelphia @ Dallas (-1)
Oakland @ Detroit (-2)
Week 13
Oakland (-5) @ Denver
Cleveland (-6) @ Los Angeles (A)
Pittsburgh @ Baltimore (-1)
Cincinnati @ Philadelphia (-5)
New York (N) (-7) @ Green Bay
Dallas @ Washington (-4)
Chicago @ San Francisco (-3)
Carolina @ Arizona (-21)
Buffalo @ New England (-1)
Indianapolis @ Houston (-18)
New Orleans (-2) @ Miami
New York (A) @ Atlanta (-13)
Jacksonville @ Tennessee (even) Game of the week
Los Angeles (N) @ Tampa Bay (-6)
Detroit @ Seattle (-1)
Kansas City @ Minnesota (-6)
Week 14
Pittsburgh (-3) @ Denver
Baltimore @ Los Angeles (A) (-2)
Oakland @ Cleveland (-7)
Kansas City @ Cincinnati (-5)
Philadelphia @ Green Bay (-7)
New York (N) (-12) @ Washington
Dallas @ Chicago (-1) Game of the week
San Francisco @ Arizona (-19)
Carolina @ Buffalo (-11)
Houston (-14) @ New England
Indianapolis @ Miami (-8)
New Orleans (-2) @ Atlanta
New York (A) @ Jacksonville (-10)
Tennessee (-1) @ Los Angeles (N)
Tampa Bay @ Seattle (-4)
Detroit (-1) @ Minnesota
Week 15
Green Bay @ Oakland (-3)
Philadelphia @ Minnesota (-2)
Cleveland (-5) @ Baltimore
Miami (-4) @ New England
Dallas @ Pittsburgh (-7)
Atlanta (-7) @ Los Angeles (N)
Arizona (-9) @ Tampa Bay
Los Angeles (A) @ Kansas City (even) Game of the week
Washington @ Detroit (-7)
Denver @ Chicago (-3)
Carolina @ New Orleans (-21)
Cincinnati @ New York (N) (-19)
Seattle (-2) @ San Francisco
Indianapolis @ Tennessee (-2)
Jacksonville @ Buffalo (-1)
New York (A) @ Houston (-23)
Week 16
Indianapolis (-2) @ New York (A)
Houston (-13) @ Seattle
Miami @ Jacksonville (even) Game of the week
Tampa Bay (-3) @ Carolina
Washington @ Atlanta (-11)
Cleveland (-7) @ Cincinnati
Kansas City @ Pittsburgh (-9)
New York (N) (-11) @ Baltimore
Minnesota @ Chicago (even)
Los Angeles (A) @ Green Bay (-8)
Buffalo @ New Orleans (-13)
New England @ Tennessee (-4)
Los Angeles (N) @ Arizona (-18)
San Francisco @ Dallas (-5)
Detroit @ Philadelphia (even)
Denver @ Oakland (-11)